Vitamin C precursor decreases stroke damage in mice
Vitamin C is unable to cross the blood-brain barrier, but the vitamin C precursor dehydroascorbic acid (DHA) can, then is converted into vitamin C within the brain. In this murine study utilizing DHA, brain damage from a stroke was lessened by giving the mice DHA. Vitamin C's antioxidant effect is thought to be responsible for the benefit.
Proceedings of the National Academy of Sciences 2001;98:11720-
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