July 4th, 2004, 12:25
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Withdrawal of Thyroid Replacement Therapy Not Necessary With Tc-99m MIBI
Thallium-201 and, recently, Tc-99m MIBI have been used in conjunction with I-131 scintigraphy for follow-up of patients with well-differentiated thyroid cancer. Insular carcinoma of the thyroid is a fairly aggressive thyroid neoplasm that is believed to arise from follicular cells and usually concentrates I-131. The authors report a patient with recurrent insular thyroid carcinoma in whom bilateral adrenal and lung metastatic lesions developed 3 years after ablative I-131 therapy for cervical lymph node and skeletal metastases. Tc-99m MIBI planar and SPECT images demonstrated these new lesions better than pretherapy I-131 scintigraphy and affords an imaging technique for post-I-131 therapy follow-up that does not require withholding thyroid hormone suppression.
Clin Nucl Med. 1995 Jan;20(1):31-6.
Tc-99m MIBI scintigraphic detection of metastatic insular thyroid carcinoma.
Zak IT, Seabold JE, Gurll NJ.
Department of Radiology, University of Iowa College of Medicine, Iowa City 52242.
http://www.ncbi.nlm.nih.gov/entrez/...st_uids=7895433
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