January 27th, 2004, 09:05
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Join Date: 2001
Posts: 1,085
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PET poorly predicts response to preoperative chemotherapy
This article found that PET scanning was poorly predictive of a good response to preoperative chemotherapy in non-small cell lung cancer patients (the positive predictive value was 43%). However, the negative predictive value was 100%. Post-chemotherapy PET was not good at determining nodal status. The authors conclude that post-chemotherapy PET is not useful in predicting response to chemotherapy. COMMENT: it should be noted, however, that PET is still useful in the initial staging of NSCLC because of its excellent ability to detect unsuspected distant metastases.
TITLE: Positron emission tomography scanning poorly predicts response to preoperative chemotherapy in non-small cell lung cancer
REF: Ann Thorac Surg 2004;77:254-259
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