Community Forum top_calendar.gif top_members.gif top_faq.gif top_search.gif top_home.gif    

Go Back   Community Forum > The Internet Medical Journal > News
User Name
Password
FAQ Members List Calendar Search Today's Posts Mark Forums Read


Reply
 
Thread Tools Search this Thread Display Modes
  #1  
Old September 20th, 2004, 13:47
sysadmin sysadmin is offline
Administrator
 
Join Date: 2001
Posts: 1,085
Exercise Testing in Women

2994 asymptomatic women, aged 30 to 80 years, without known coronary artery disease, were examined with a near-maximal Bruce-protocol treadmill test. Data was obtained during the years 1972-1976, with follow-up through 1995. There were 427 (14%) deaths during 20 years of follow-up, of which 147 were due to cardiovascular causes. Low exercise capacity, low heart rate recovery (HRR), and not achieving target heart rate were independently associated with increased all-cause and cardiovascular mortality. There was no increased cardiovascular death risk for exercise-induced ST-segment depression (age-adjusted hazard ratio, 1.02; 95% confidence interval [CI], 0.57-1.80; P =.96). The age-adjusted hazard ratio for cardiovascular death for every metabolic equivalent (MET) decrement in exercise capacity was 1.20 (95% CI, 1.18-1.30; P<.001); for every 10 beats per minute decrement in HRR, the hazard ratio was 1.36 (95% CI, 1.19-1.55; P<.001). After adjusting for multiple other risk factors, women who were below the median for both exercise capacity and HRR had a 3.5-fold increased risk of cardiovascular death (95% CI, 1.57-7.86; P =.002) compared with those above the median for both variables. Among women with low risk Framingham scores, those with below median levels of both exercise capacity and HRR had significantly increased risk compared with women who had above median levels of these 2 exercise variables, 44.5 and 3.5 cardiovascular deaths per 10 000 person-years, respectively (hazard ratio for cardiovascular death, 12.93; 95% CI, 5.62-29.73; P<.001). CONCLUSION: The prognostic value of exercise testing in asymptomatic women derives not from electrocardiographic ischemia but from fitness-related variables.

COMMENT: this study found that exercise capacity and heart rate recovery was more important than ST changes in the EKG during maximal stress.

JAMA. 2003 Sep 24;290(12):1600-7.

Ability of exercise testing to predict cardiovascular and all-cause death in asymptomatic women: a 20-year follow-up of the lipid research clinics prevalence study.

Mora S, Redberg RF, Cui Y, Whiteman MK, Flaws JA, Sharrett AR, Blumenthal RS.

Ciccarone Preventive Cardiology Center, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, Md 21287, USA.

http://www.ncbi.nlm.nih.gov/entrez/...t_uids=14506119
Reply With Quote
Reply


Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is On
HTML code is On
Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
Exercise Better Than Angioplasty sysadmin News 0 July 12th, 2004 16:46
New Research Gives a Scientific Basis for Frequency of PSA Testing sysadmin News 0 July 8th, 2004 10:28
Prognosis in Women With Myocardial Ischemia but no Obstructive Coronary Disease sysadmin News 0 June 27th, 2004 10:19
Screen All Women With Treadmill Test sysadmin News 0 June 4th, 2004 21:40
Multiple short bursts of exercise as effective as sustained exercise sysadmin News 0 October 22nd, 2001 22:37


All times are GMT -8. The time now is 03:35.


Powered by: vBulletin Version 3.0.3
Copyright ©2000 - 2018, Jelsoft Enterprises Ltd.



Be careful about reading health books. You may die of a misprint.  
- Mark Twain (1835 - 1910)

We are committed to your good health. That means that while we provide editorial medical information, we must insist that you work with your own doctor in regards to your personal health issues. All content on Medjournal.Com is strictly editorial. It constitutes medical opinion, NOT ADVICE. We do not endorse or recommend the content of Medjournal.com or the sites that are linked FROM or TO Medjournal.com. Use common sense by consulting with your doctor before making any lifestyle changes or other medical decisions based on the content of these web pages. Medjournal.Com and the Internet Medical Journal shall not be held liable for any errors in content, advertising, or for any actions taken in reliance thereon.