Community Forum top_calendar.gif top_members.gif top_faq.gif top_search.gif top_home.gif    

Go Back   Community Forum > The Internet Medical Journal > News
User Name
Password
FAQ Members List Calendar Search Today's Posts Mark Forums Read


Reply
 
Thread Tools Search this Thread Display Modes
  #1  
Old May 9th, 2005, 07:32
sysadmin sysadmin is offline
Administrator
 
Join Date: 2001
Posts: 1,085
Noninvasive assessment of coronary microvascular dysfunction using Tc-99m tetrofosmin

OBJECTIVE: Evaluate whether Tc-99m tetrofosmin (TF) SPECT myocardial perfusion imaging can predict coronary microvascular dysfunction in patients with acute myocardial infarction. METHODS AND RESULTS: Immediately after percutaneous coronary intervention in 25 patients with an acute myocardial infarction, SPECT imaging was performed, and a regional severity score index (RSSI) was calculated. Using a Doppler guidewire, the deceleration time of diastolic flow velocity (DDT) after percutaneous coronary intervention was calculated. A DDT of 600 milliseconds or less was defined as an indicator of coronary microvascular dysfunction. A regional wall motion score index (RWMSI) was obtained during the chronic phase. The correlation between RSSI and DDT was good(r = -0.68, P < .01). The RSSI cutoff value of 1.9 or greater had a sensitivity of 100% and specificity of 71% in predicting DDT. Those with poor scintigraphic coronary microvascular function (RSSI > or =1.9, n = 7) had a significantly shorter DDT (P = .0003), a lower frequency of early systolic retrograde flow (P = .0038), and greater chronic RWMSI (P = .0015) than the group with good scintigraphic coronary microvascular function. CONCLUSIONS: SPECT myocardial perfusion and function scanning immediately after percutaneous coronary intervention in patients with acute myocardial infarction is a useful noninvasive method for evaluating coronary microvascular dysfunction.

COMMENT: an abnormal SPECT myocardial perfusion and function scan immediately after percutaneous coronary intervention can be an early indicator of coronary microvascular dysfunction.

J Nucl Cardiol. 2004 Sep-Oct;11(5):562-9.

Noninvasive assessment of coronary microvascular dysfunction using Tc-99m tetrofosmin SPECT in patients with acute myocardial infarction.

Abe Y, Kondo M, Kubota T, Matsuoka R, Araki M, Doyama K, Tanio H.

Division of Cardiology, Shimada Municipal Hospital, Shimada City, Shizuoka 427-8502, Japan.
Reply With Quote
Reply


Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is On
HTML code is On
Forum Jump



All times are GMT -8. The time now is 11:12.


Powered by: vBulletin Version 3.0.3
Copyright ©2000 - 2018, Jelsoft Enterprises Ltd.



Be careful about reading health books. You may die of a misprint.  
- Mark Twain (1835 - 1910)

We are committed to your good health. That means that while we provide editorial medical information, we must insist that you work with your own doctor in regards to your personal health issues. All content on Medjournal.Com is strictly editorial. It constitutes medical opinion, NOT ADVICE. We do not endorse or recommend the content of Medjournal.com or the sites that are linked FROM or TO Medjournal.com. Use common sense by consulting with your doctor before making any lifestyle changes or other medical decisions based on the content of these web pages. Medjournal.Com and the Internet Medical Journal shall not be held liable for any errors in content, advertising, or for any actions taken in reliance thereon.