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Old June 22nd, 2003, 15:47
sysadmin sysadmin is offline
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Impact of Prostate Cancer Screening

This study created simulated models of the effect of prostate cancer screening upon: 1) the lead time in diagnosis gained, and 2) the overdetection rate. It used data from the Rotterdam section of the European Randomized Study of Screening for Prostate Cancer (with the prostate specific antigen test). It looked at several different models: (1) screening once at age 55, (2) screening once at age 75, (3) screening every 4 years from age 55 to age 67, and (4) annual screening from age 55 to age 67. Their results support less than annual screening for prostate cancer. Comment: The overdetection rate is the percent of men diagnosed with prostate cancer who otherwise would never have been diagnosed (because it was essentially a benign condition). The overdetection rates varied from 25% to 50% in order to gain a lead time of up to 12 years. It looks either a single PSA screen at age 55, or not screening at all is the winner. Still, such modelling is frought with the potential for error, so the implications for current practice are unclear. Also visit Canada.com article

[ Cancer Spectrum: Draisma et al., pp. 868-878. ]


Last edited by sysadmin : June 22nd, 2003 at 15:47.
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