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July 4th, 2003, 20:17
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Join Date: 2001
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PET Effective in Staging Nodes of < 1 cm
TITLE: Comparative Efficacy of Positron Emission Tomography With Fluorodeoxyglucose in Evaluation of Small (<1 cm), Intermediate (1 to 3 cm), and Large (>3 cm) Lymph Node Lesions
REF: Chest. 2000;117:773-778 http://www.chestjournal.org/cgi/con...pe2=tf_ipsecsha
STUDY TYPE: prospective enrollment of consecutive patients
PATIENTS: 118 consecutive patients with NSCLC
FINDINGS: PET was sensitive in detecting both small (<1 cm) and large (>3 cm) nodes. For nodes < 1 cm in size, FDG PET sensitivity, specificity, and accuracy was 97%, 82%, and 95%
CONCLUSION: PET is useful in the evaluation of both large and small nodes.
COMMENT: this study used 2D scanning using a GE Advance PET scanner. Several literature reviews state that PET cannot accurately detect nodes < 1 cm in size, but these reviews include both coincidence imaging and dedicated PET imaging. Dedicating PET imaging -- such as is performed by the GE Advance PET camera -- is much more sensitive than coincident systems. Guidelines need to be updated to take into account that coincidence imaging is only rarely used in comparison to dedicated PET imaging.
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