This review examined the evidence for myocardial perfusion scintigraphy (MPS) in patients with known or suspected coronary artery disease. It is frome a consensus conference organized by the British Cardiac Society, the British Nuclear Cardiology Society and the British Nuclear Medicine Society. The review is endorsed by the Royal College of Physicians of London and the Royal College of Radiologists. MPS is a well-established, non-invasive imaging technique with a large body of evidence to support its effectiveness in the diagnosis and management of angina and myocardial infarction. It is more accurate than the exercise ECG in detecting myocardial ischaemia and it is the single most powerful technique for predicting future coronary events. Evidence supports the cost-effectiveness associated with MPS use. In patients presenting with stable or acute chest pain, strategies of investigation involving MPS are more cost-effective than those not using the technique. MPS also has particular advantages over alternative techniques in the management of a number of patient subgroups, including women, the elderly and those with diabetes. Its use will have a favorable impact on cost-effectiveness in these groups.

Eur J Nucl Med Mol Imaging. 2004 Feb;31(2):261-91.

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