The authors of this study conclude that women with normal coronary catheterizations still may have significant coronary disease, as diagnosed by a stress-induced reduction in myocardial phosphocreatine–adenosine triphosphate ratio by phosphorus-31 nuclear magnetic resonance spectroscopy. COMMENT: the statistics in this study are very fragile, with only 14 women being in the group of normal coronary angiograms but abnormal MR spectroscopy. The findings are interesting, but very preliminary.

Prognosis in Women With Myocardial Ischemia in the Absence of Obstructive Coronary Disease

Circulation. 2004;109:2993-2999

B. Delia Johnson, PhD; Leslee J. Shaw, PhD; Steven D. Buchthal, PhD; C. Noel Bairey Merz, MD; Hee-Won Kim, PhD; Katherine N. Scott, PhD; Mark Doyle, MD; Marian B. Olson, MS; Carl J. Pepine, MD; Jan den Hollander, MD; Barry Sharaf, MD; William J. Rogers, MD; Sunil Mankad, MD; John R. Forder, PhD; Sheryl F. Kelsey, PhD; Gerald M. Pohost, MD

http://circ.ahajournals.org/cgi/con...act/109/24/2993