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February 16th, 2003, 12:39
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Join Date: 2001
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2002.12.01 Cardiovascular Disease News
Saturday, December 21, 2002
NEJM: C-Reactive Protein and Low-Density Lipoprotein Cholesterol Levels Both Help in the Prediction of First Cardiovascular Events NEJM -- Abstracts: Ridker et al. 347 (20): 1557 ] posted at 10:45 AM
by Tom Heston, MD
Wednesday, December 11, 2002
Conversion of Atrial Fibrillation to Sinus Does Not Improve Survival Compared to Rate Control Only This study of 4060 patients with atrial fibrillation who had a high risk of stroke or death. One group was assigned to rhythm-control therapy, the other to rate-control therapy. The researchers conclude that the rhythm-control therapy has no survival advantage over the rate-control strategy. In fact, side-effects from medications used in the rhythm-control group may make a rate-control strategy better in terms of health benefits. Comment: a rate-control strategy also may be significantly less expensive, as well as associated with fewer side-effects and an equal mortality rate. [ NEJM 2002, Volume 347:1825-1833 ] posted at 6:12 PM
by Tom Heston, MD
Tuesday, December 10, 2002
Drug Eluting Stents This editorial covers the status of drug eluting stents, the cost savings, and future. The author notes that the current rate of reintervention after angioplasty is 6% in the UK. [ bmj.com Jenkins et al. 325 (7376): 1315 ] posted at 9:14 AM
by Tom Heston, MD
Tuesday, December 03, 2002
Coffee Consumption Shown to Increase Homocysteine Levels This randomized study of 48 volunteers found that coffee (0.45 L, ~ 1.5 cups) raised homocysteine levels by 0.9 umol/L (an 11% increase) at 4 hours after consumption. The researchers looked specifically at whether or not caffeine was the responsible ingredient, and found that caffeine was only partly responsible for the elevation in homocysteine levels, raising the plasma concentration by 0.4 umol/L (a 5% increase) whereas coffee raised homocysteine by 0.9 umol/L. Comment: this is an interesting finding, and it is worthwhile looking into the effects of caffeinated soft drinks on homocysteine levels as well. [ AJCN -- Abstracts: Verhoef et al. 76 (6): 1244 ] posted at 1:28 PM
by Tom Heston, MD
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