Causes of acute severe generalised peripheral neuropathy


CausePredominantly motorMixedPredominantly sensory

Guillain-Barré syndrome++ ---
Vasculitis ---+ ---
Diabetes mellitus ---++
Drugs* ---++
Porphyria+ --- ---
Diphtheria ---+ ---
Paraneoplastic neuropathy ---++
Acute idiopathic sensory neuronopathy --- ---+
Critical illness++ ---

* For example, nitrofurantoin, vincristine, cisplatin, and reverse transcriptase inhibitors.