June 29th, 2004, 14:30
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Estrogen Supplementation Increases Mental Decline in Elderly Women
This study of 2808 women found that estrogen supplementation with conjugated equine estrogens increased the likelihood of a major decline in mental abilities. COMMENT: this is yet another study showing the negative effects of supplemental estrogen. Possibly, this effect upon cognition is due to the increase in clotting risk from estrogen.
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Conjugated equine estrogens and global cognitive function in postmenopausal women: Women's Health Initiative Memory Study.
Espeland MA, Rapp SR, Shumaker SA, Brunner R, Manson JE, Sherwin BB, Hsia J, Margolis KL, Hogan PE, Wallace R, Dailey M, Freeman R, Hays J; Women's Health Initiative Memory Study.
JAMA. 2004 Jun 23;291(24):2959-68.
http://jama.ama-assn.org/cgi/content/full/291/24/2959
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